Khattab, A. D., Rawlings, B. and Ali, I.S., 2006. Care of patients with haemoglobin abnormalities: history and biology. British Journal of Nursing, 15 (18), pp. 994-998.
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Haemoglobinopathies refer to a range of genetically inherited disorders of red blood cell haemoglobin and include sickle cell disorders and thalassaemias. They occur most commonly in populations whose ancestors come from Africa, Asia, Mediterranean Islands, and the Middle and Far East. Haemoglobin (Hb) abnormalities (or haemoglobinopathies) are caused by (i) abnormalities of the protein structure; (ii) imbalanced globin chain production owing to reduced rate of synthesis of normal a or b globin chains; or (iii) a combination of the two. This article will focus on the biological basis of sickle cell disorders and will discuss the history and pathology of the conditions.
|Uncontrolled Keywords:||Sickle cell disease, pathophysiology, clinical features, complications|
|Subjects:||Technology > Medicine and Health|
|Group:||School of Health and Social Care > Centre for Postgraduate Medical Research and Education|
|Deposited By:||Professor Ahmed Khattab|
|Deposited On:||06 Oct 2009 20:24|
|Last Modified:||07 Mar 2013 15:15|
Available Versions of this Item
- Care of patients with haemoglobin abnormalities: history and biology. (deposited 25 Apr 2007)
- Care of patients with haemoglobin abnormalities: history and biology. (deposited 06 Oct 2009 20:24) [Currently Displayed]
- Care of patients with haemoglobin abnormalities: history and biology. (deposited 06 Oct 2009 20:23)
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