Kumar, N., Jivan, S., Thomas, P. and McLure, H., 2006. Sub-Tenon's anesthesia with aspirin, warfarin, and clopidogrel. Journal of Cataract & Refractive Surgery, 32 (6), pp. 1022-1025.
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Official URL: http://dx.doi.org/10.1016/j.jcrs.2006.02.035
Purpose To review the frequency of hemorrhagic complications with sub-Tenon's anesthesia in patients on aspirin, warfarin or clopidogrel. Setting St. James's University Hospital, Leeds, United Kingdom. Methods Data were collected prospectively for patients having elective phacoemulsification under sub-Tenon's anesthesia. Seventy-five patients were on aspirin, 65 were on warfarin, and 40 were on clopidogrel. Seventy-five patients on no anticoagulants were used as the control group. No changes in the anticoagulant regimen were made prior to surgery. Results No sight-threatening hemorrhagic complications were noted, and no surgery was postponed or cancelled due to an anesthesic complication. Subconjunctival hemorrhage occurred in 19% in the control group, 40% in the clopidogrel group, 35% in the warfarin group, and 21% in the aspirin group. The warfarin and clopidogrel groups had the highest incidence of subconjunctival hemorrhage (P<.05). The incidence of hemorrhages involving more than 1 quadrant was highest in these 3 groups; however, this did not achieve statistical significance (P = .37, Fisher exact test). Conclusion Data from this study support the continued use of anticoagulant agents among routine users during cataract surgery using a sub-Tenon's block.
|Subjects:||Technology > Medicine and Health > Medicine and Surgery|
|Group:||School of Health and Social Care > Centre for Social Work and Social Policy|
|Deposited By:||INVALID USER|
|Deposited On:||03 Sep 2008 15:06|
|Last Modified:||07 Mar 2013 14:50|
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