Maternal vitamin D status has no effect on the ontogeny of calcium-binding proteins in the duodenum, kidney and cerebellum of fetal mice.

Shamley, D., Buffenstein, R. and Pettifor, J., 1993. Maternal vitamin D status has no effect on the ontogeny of calcium-binding proteins in the duodenum, kidney and cerebellum of fetal mice. Journal of Endocrinology, 139 (3), pp. 473-478.

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Official URL: http://joe.endocrinology-journals.org/cgi/search?s...

Abstract

The effects of vitamin D3 deficiency on the ontogeny of calcium-binding proteins (CaBPs) and the vitamin D receptor in the duodenum, kidney and cerebellum of the mouse were examined. Maternal vitamin D status did not affect the time of appearance of the fetal 28 kDa CaBP (CaBP-D28k) in the cerebellum, kidney and duodenum, and the 9 kDa CaBP (CaBP-D9k) in the intestine and kidney. Vitamin D receptor was undetectable in all fetal tissues, regardless of maternal vitamin D status, at all stages of gestation examined. Thus it appears that maternal vitamin D status does not affect the ontogeny of CaBP-D9k or CaBP-D28k in the mouse fetus. The factors that influence the appearance of calbindins in the fetus are unclear

Item Type:Article
ISSN:0022-0795
Subjects:Technology > Medicine and Health > Medicine and Surgery
Group:School of Health and Social Care > Centre for Postgraduate Medical Research and Education
ID Code:7152
Deposited By:INVALID USER
Deposited On:08 Feb 2009 14:00
Last Modified:07 Mar 2013 14:55
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