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ToolsHawton, A., Goodwin, E., Boddy, K., Freeman, J., Thomas, S., Chataway, J. and Green, C., 2022. Measuring the cost-effectiveness of treatments for people with multiple sclerosis: Beyond quality-adjusted life-years. Multiple Sclerosis Journal, 28 (3), 346-351.
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Abstract
BACKGROUND: It is a familiar story. A promising multiple sclerosis (MS) treatment clears the three regulatory hurdles of safety, quality and efficacy, only to fall at the fourth: cost-effectiveness. This has led to concerns about the validity of the measures typically used to quantify treatment effects in cost-effectiveness analyses and in 2012, in the United Kingdom, the National Institute for Health and Care Excellence called for an improvement in the cost-effectiveness framework for assessing MS treatments. OBJECTIVE AND METHODS: This review describes what is meant by cost-effectiveness in health/social care funding decision-making, and usual practice for assessing treatment benefits. RESULTS: We detail the use of the quality-adjusted life-year (QALY) in resource allocation decisions, and set out limitations of this approach in the context of MS. CONCLUSION: We conclude by highlighting methodological and policy developments which should aid addressing these limitations.
| Item Type: | Article |
|---|---|
| ISSN: | 1352-4585 |
| Uncontrolled Keywords: | Multiple sclerosis ; cost-effectiveness ; cost-effectiveness analysis ; health-related quality of life ; quality of life ; quality-adjusted life-years |
| Group: | Faculty of Health & Social Sciences |
| ID Code: | 34551 |
| Deposited By: | Symplectic RT2 |
| Deposited On: | 16 Sep 2020 14:27 |
| Last Modified: | 22 Mar 2022 13:44 |
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