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Store operated calcium entry (SOCE) mediates insect nephrocyte clearance function.

Sivakumar, S., Clarke, C. and Hartley, P. S., 2021. Store operated calcium entry (SOCE) mediates insect nephrocyte clearance function. In: British Society for Cell Biology Dynamic Cell IV, 14-19 March 2021, Online.

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Abstract

Insect nephrocytes are highly endocytic cells which remove proteins and xenotoxins from circulation (Figure 1). They express evolutionarily conserved ‘slit diaphragms’ at their surface; ultrastructures also expressed by mammalian kidney podocytes. Identifying nephrocyte signalling pathways is therefore important as they are relevant to clearance and renal function in many species, including humans. Establishing a method to investigate calcium signalling in nephrocytes was attempted in the current work.

Item Type:Conference or Workshop Item (Poster)
Group:Faculty of Science & Technology
ID Code:36715
Deposited By: Symplectic RT2
Deposited On:07 Mar 2022 15:46
Last Modified:14 Mar 2022 14:33

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