Brewin, M., Docherty, S., Heaslip, V., Breheny, K., Pleat, J., Rhodes, S., van Zuijlen, P. P.M. and Shah, M., 2022. Early Laser for Burn Scars (ELABS): protocol for a multi-centre randomised, controlled trial of both the effectiveness and cost-effectiveness of the treatment of hypertrophic burn scars with Pulsed Dye Laser and standard care compared to standard care alone [version 1; peer review: 2 approved]. NIHR Open Research, 2, 1.
Full text available as:
|
PDF
Published ELABS protocol.pdf - Published Version Available under License Creative Commons Attribution. 672kB | |
Copyright to original material in this document is with the original owner(s). Access to this content through BURO is granted on condition that you use it only for research, scholarly or other non-commercial purposes. If you wish to use it for any other purposes, you must contact BU via BURO@bournemouth.ac.uk. Any third party copyright material in this document remains the property of its respective owner(s). BU grants no licence for further use of that third party material. |
DOI: 10.3310/nihropenres.13234.1
Abstract
This paper outlines the protocol for a study that is being carried out at multiple centres across the UK in the next three years. It is a Research for Patient Benefit (RfPB) study funded by the National Institute for Healthcare Research (NIHR). The aim is to assess the effectiveness of treating hypertrophic burns scars with pulsed dye laser (PDL) at an early stage of scar formation. The objective is to improve Quality of Life for the patient by improving both the appearance and quality of burn scarring, as well as reducing its psychological impact. This is a parallel-arm randomised, controlled trial to compare PDL and standard care against standard care alone. The difference is measured between baseline and six-month follow-up. Recruits are within three months of healing from a burn injury; with wounds showing a defined potential for hypertrophic scarring. A total of 120 patients are recruited in a multi-centre study; with randomisation in a 1:1 allocation to each arm. The treatment arm receives 3 PDL treatments at six-week intervals in addition to standard care, whereas the control arm receives standard care alone. The primary outcome is the patient-rated part of the Patient and Observer Scar Scale (POSAS). Psychological and psycho-social impact is evaluated using the CARe burn scale (UWE, Bristol) and Quality Adjusted Life Years (QALY) is determined using the Short-Form Health Survey (SF-12). The study evaluates both the cost-effectiveness through an economic analysis and the patient-reported experience of the treatment by phone interviews.
Item Type: | Article |
---|---|
ISSN: | 2633-4402 |
Uncontrolled Keywords: | CARe Burn Scale;Early treatment;Health Economic Analysis;Hypertrophic Burn Scars;POSAS;Pulsed Dye Laser (PDL);Quality of Life;RCT |
Group: | Faculty of Health & Social Sciences |
ID Code: | 36863 |
Deposited By: | Symplectic RT2 |
Deposited On: | 25 Apr 2022 08:44 |
Last Modified: | 25 Apr 2022 08:44 |
Downloads
Downloads per month over past year
Repository Staff Only - |