Lead exposure in adult males in urban Transvaal Province, South Africa during the apartheid era.

Hess, C., Cooper, M.J., Smith, M.J., Trueman, C. and Schutkowski, H., 2013. Lead exposure in adult males in urban Transvaal Province, South Africa during the apartheid era. PLoS One, 8 (3), e58146.

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C Hess et al PLoS ONE proofed confirmed.pdf - Accepted Version

Lead_exposure_in_adult_males_in_urban_Transvaal.pdf - Published Version


DOI: 10.1371/journal.pone.0058146


Human exposure to lead is a substantial public health hazard worldwide and is particularly problematic in the Republic of South Africa given the country’s late cessation of leaded petrol. Lead exposure is associated with a number of serious health issues and diseases including developmental and cognitive deficiency, hypertension and heart disease. Understanding the distribution of lifetime lead burden within a given population is critical for reducing exposure rates. Femoral bone from 101 deceased adult males living in urban Transvaal Province (now Gauteng Province), South Africa between 1960 and 1998 were analyzed for lead concentration by Inductively Coupled Plasma Mass Spectrometry (ICP-MS). Of the 72 black and 29 white individuals sampled, chronic lead exposure was apparent in nearly all individuals. White males showed significantly higher median bone lead concentration (ME = 10.04 µg·g−1), than black males (ME = 3.80 µg·g−1) despite higher socioeconomic status. Bone lead concentration covaries significantly, though weakly, with individual age. There was no significant temporal trend in bone lead concentration. These results indicate that long-term low to moderate lead exposure is the historical norm among South African males. Unexpectedly, this research indicates that white males in the sample population were more highly exposed to lead.

Item Type:Article
Group:Faculty of Science and Technology
ID Code:20695
Deposited By: Unnamed user with email symplectic@symplectic
Deposited On:16 Feb 2013 16:53
Last Modified:09 Sep 2015 11:59


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