Wee, M. Y., Tuckey, J. P., Thomas, P. and Burnard, S., 2011. The IDvIP trial: a two-centre randomised double-blind controlled trial comparing intramuscular diamorphine and intramuscular pethidine for labour analgesia. BMC Pregnancy and Childbirth, 11 (51), pp. 1-8.
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The IDvIP trial: a two-centre randomised double-blind controlled trial comparing intramuscular diamorphine and intramuscular pethidine for labour analgesia..pdf
Intramuscular pethidine is routinely used throughout the UK for labour analgesia. Studies have suggested that pethidine provides little pain relief in labour and has a number of side effects affecting mother and neonate. It can cause nausea, vomiting and dysphoria in mothers and can cause reduced fetal heart rate variability and accelerations. Neonatal effects include respiratory depression and impaired feeding. There are few large studies comparing the relative side effects and efficacy of different opioids in labour. A small trial comparing intramuscular pethidine with diamorphine, showed diamorphine to have some benefits over pethidine when used for labour analgesia but the study did not investigate the adverse effects of either opioid.
|Uncontrolled Keywords:||Analgesia, Obstetrical ; Analgesics, Opioid ; Apgar Score ; Cardiotocography ; Double-Blind Method ; Feeding Behavior ; Female ; Heroin ; Humans ; Infant, Newborn ; Injections, Intramuscular ; Intensive Care, Neonatal ; Labor Pain ; Meperidine ; Nausea ; Oxygen ; Patient Satisfaction ; Pregnancy ; Resuscitation ; Vomiting|
|Group:||School of Health and Social Care|
|Deposited By:||Unnamed user with email symplectic@symplectic|
|Deposited On:||02 Jul 2015 10:42|
|Last Modified:||06 Jul 2015 14:47|
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