Appleton, K., Woodside, J.V., Arveiler, D., Haas, B., Amouyel, P., Montaye, M., Ferrieres, J., Ruidavets, J.B., Yarnell, J.W.G., Kee, F., Evans, A., Bingham, A., Ducimetiere, P., Patterson, C.C. and PRIME study group, , 2016. A Role for Behavior in the Relationships Between Depression and Hostility and Cardiovascular Disease Incidence, Mortality, and All-Cause Mortality: the Prime Study. Annals of Behavioral Medicine.
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BACKGROUND: Behavioral factors are important in disease incidence and mortality and may explain associations between mortality and various psychological traits. PURPOSE: These analyses investigated the impact of behavioral factors on the associations between depression, hostility and cardiovascular disease(CVD) incidence, CVD mortality, and all-cause mortality. METHODS: Data from the PRIME Study (N = 6953 men) were analyzed using Cox proportional hazards models, following adjustment for demographic and biological CVD risk factors, and other psychological traits, including social support. RESULTS: Following initial adjustment, both depression and hostility were significantly associated with both mortality outcomes (smallest SHR = 1.24, p < 0.001). Following adjustment for behavioral factors, all relationships were attenuated both when accounting for and not accounting for other psychological variables. Associations with all-cause mortality remained significant (smallest SHR = 1.14, p = 0.04). Of the behaviors included, the most significant contribution to outcomes was found for smoking, but a role was also found for fruit and vegetable intakes and high alcohol consumption. CONCLUSIONS: These findings demonstrate well-known associations between depression, hostility, and mortality and suggest the potential importance of behaviors in explaining these relationships.
|Uncontrolled Keywords:||Behavior ; Cardiovascular disease ; Depression ; Hostility ; Mortality ; Social support|
|Group:||Faculty of Science and Technology|
|Deposited By:||Unnamed user with email symplectic@symplectic|
|Deposited On:||22 Mar 2016 10:49|
|Last Modified:||22 Mar 2016 10:49|
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