Effect of eccentric exercise with reduced muscle glycogen on plasma interleukin-6 and neuromuscular responses of m. quadriceps femoris.

Gavin, J., Myers, S.D. and Willems, M.E.T., 2016. Effect of eccentric exercise with reduced muscle glycogen on plasma interleukin-6 and neuromuscular responses of m. quadriceps femoris. Journal of Applied Physiology.

Full text available as:

[img] PDF
Gavin et al Figure 1 R2.pdf - Accepted Version
Restricted to Repository staff only until 5 May 2017.
Available under License Creative Commons Attribution Non-commercial No Derivatives.

86kB
[img] PDF
Gavin et al Figure 2 R2.pdf - Accepted Version
Restricted to Repository staff only until 5 May 2017.
Available under License Creative Commons Attribution Non-commercial No Derivatives.

18kB
[img] PDF
Gavin et al Figure 3 R2.pdf - Accepted Version
Restricted to Repository staff only until 5 May 2017.
Available under License Creative Commons Attribution Non-commercial No Derivatives.

20kB
[img] PDF
Gavin et al Figure 4 R2.pdf - Accepted Version
Restricted to Repository staff only until 5 May 2017.
Available under License Creative Commons Attribution Non-commercial No Derivatives.

17kB
[img] PDF
Clean Gavin et al R2-1 (1).pdf - Accepted Version
Restricted to Repository staff only until 5 May 2017.
Available under License Creative Commons Attribution Non-commercial No Derivatives.

250kB

DOI: 10.1152/japplphysiol.00383.2015

Abstract

Eccentric exercise can result in muscle damage and interleukin-6 (IL-6) secretion. Glycogen availability is a potent stimulator of IL-6 secretion. We examined effects of eccentric exercise in a low glycogen state on neuromuscular function and plasma IL-6 secretion. Twelve active males (23 ± 4 years, 179 ± 5 cm, 77 ± 10 kg) completed two downhill treadmill runs (gradient, -12%, 5x8 min; speed, 12.1 ± 1.1 km∙h-1) with normal (NG) and reduced muscle glycogen (RG) in randomized order and at least six weeks apart. Muscle glycogen was reduced using an established cycling protocol until exhaustion and dietary manipulation the evening before the morning run. Physiological responses were measured up to 48 h after the downhill runs. During recovery, force deficits of m. quadriceps femoris by maximal isometric contractions were similar. Changes in low-frequency fatigue were larger with RG. Voluntary activation and plasma IL-6 levels were similar in recovery between conditions. It is concluded that unaccustomed, damaging eccentric exercise with low muscle glycogen of the m. quadriceps femoris: i) exacerbated low-frequency fatigue, but ii) had no additional effect on IL-6 secretion. Neuromuscular impairment after eccentric exercise with low muscle glycogen appears to have a greater peripheral component in early recovery.

Item Type:Article
ISSN:8750-7587
Uncontrolled Keywords:eccentric exercise; muscle glycogen; interleukin-6
Subjects:UNSPECIFIED
Group:Faculty of Management
ID Code:23571
Deposited By: Unnamed user with email symplectic@symplectic
Deposited On:13 May 2016 11:06
Last Modified:13 May 2016 11:06

Downloads

Downloads per month over past year

More statistics for this item...
Repository Staff Only -