An exploration of men's experiences of undergoing active surveillance for favourable-risk prostate cancer: A mixed methods study protocol.

Ruane-McAteer, E., O'Sullivan, J., Porter, S., Venderbos, L. and Prue, G., 2016. An exploration of men's experiences of undergoing active surveillance for favourable-risk prostate cancer: A mixed methods study protocol. BMC Cancer, 16 (1), p. 586.

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DOI: 10.1186/s12885-016-2605-6

Abstract

BACKGROUND: Prostate cancer is one of the most common male cancers worldwide. Active Surveillance (AS) has been developed to allow men with lower risk disease to postpone or avoid the adverse side effects associated with curative treatments until the disease progresses. Despite the medical benefits of AS, it is reported that living with untreated cancer can create a significant emotional burden for patients. METHODS/DESIGN: The aim of this study is to gain insight into the experiences of men eligible to undergo AS for favourable-risk PCa. This study has a mixed-methods sequential explanatory design consisting of two phases: quantitative followed by qualitative. Phase 1 has a multiple point, prospective, longitudinal exploratory design. Ninety men diagnosed with favourable-risk prostate cancer will be assessed immediately post-diagnosis (baseline) and followed over a period of 12 months, in intervals of 3 month. Ninety age-matched men with no cancer diagnosis will also be recruited using peer nomination and followed up in the same 3 month intervals. Following completion of Phase 1, 10-15 AS participants who have reported both the best and worst psychological functioning will be invited to participate in semi-structured qualitative interviews. Phase 2 will facilitate further exploration of the quantitative results and obtain a richer understanding of participants' personal interpretations of their illness and psychological wellbeing. DISCUSSION: To our knowledge, this is the first study to utilise early baseline measures; include a healthy comparison group; calculate sample size through power calculations; and use a mixed methods approach to gain a deeper more holistic insight into the experiences of men diagnosed with favourable-risk prostate cancer.

Item Type:Article
ISSN:1471-2407
Uncontrolled Keywords:Active surveillance; Anxiety; Depression; Mixed methods; Prostate cancer; Psychological adjustment; Quality of life; Uncertainty
Subjects:UNSPECIFIED
Group:Faculty of Health & Social Sciences
ID Code:24701
Deposited By: Unnamed user with email symplectic@symplectic
Deposited On:07 Sep 2016 08:22
Last Modified:07 Sep 2016 08:22

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