Neandertal and Denisovan DNA from Pleistocene sediments.

Slon, V., Hopfe, C., Weiß, C.L., Mafessoni, F., de la Rasilla, M., Lalueza-Fox, C., Rosas, A., Soressi, M., Knul, M.V., Miller, R., Stewart, J. R., Derevianko, A.P., Jacobs, Z., Li, B., Roberts, R.G., Shunkov, M.V., de Lumley, H., Perrenoud, C, Gušić, I., Kućan, Z., Rudan, P., Aximu-Petri, A., Essel, E., Nagel, S., Nickel, B., Schmidt, A., Prüfer, K., Kelso, J., Burbano, H.A., Pääbo, S. and Meyer, M., 2017. Neandertal and Denisovan DNA from Pleistocene sediments. Science, 356 (6338), pp. 605-608.

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DOI: 10.1126/science.aam9695

Abstract

Although a rich record of Pleistocene human-associated archaeological assemblages exists, the scarcity of hominin fossils often impedes the understanding of which hominins occupied a site. Using targeted enrichment of mitochondrial DNA we show that cave sediments represent a rich source of ancient mammalian DNA that often includes traces of hominin DNA, even at sites and in layers where no hominin remains have been discovered. By automation-assisted screening of numerous sediment samples we detect Neandertal DNA in eight archaeological layers from four caves in Eurasia. In Denisova Cave we retrieved Denisovan DNA in a Middle Pleistocene layer near the bottom of the stratigraphy. Our work opens the possibility to detect the presence of hominin groups at sites and in areas where no skeletal remains are found.

Item Type:Article
ISSN:0036-8075
Additional Information:This is the author’s version of the work. It is posted here by permission of the AAAS for personal use, not for redistribution. The definitive version was published in Science eaam9695 27.4.17. DOI: 10.1126/science.aam9695
Group:Faculty of Science & Technology
ID Code:29206
Deposited By: Unnamed user with email symplectic@symplectic
Deposited On:12 May 2017 09:06
Last Modified:19 Jul 2017 15:17

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