Greville-Harris, M., Bostock, J., Din, A., Graham, C.A., Lewith, G., Liossi, C., O'Riordan, T., White, P., Yardley, L. and Bishop, F.L., 2016. Informing Patients About Placebo Effects: Using Evidence, Theory, and Qualitative Methods to Develop a New Website. JMIR Research Protocols, 5 (2), -.
Full text available as:
|
PDF (OPEN ACCESS ARTICLE)
Greville-Harris et al. 2016 research protocol.pdf - Published Version Available under License Creative Commons Attribution. 3MB | |
Copyright to original material in this document is with the original owner(s). Access to this content through BURO is granted on condition that you use it only for research, scholarly or other non-commercial purposes. If you wish to use it for any other purposes, you must contact BU via BURO@bournemouth.ac.uk. Any third party copyright material in this document remains the property of its respective owner(s). BU grants no licence for further use of that third party material. |
DOI: 10.2196/resprot.5627
Abstract
BACKGROUND: According to established ethical principles and guidelines, patients in clinical trials should be fully informed about the interventions they might receive. However, information about placebo-controlled clinical trials typically focuses on the new intervention being tested and provides limited and at times misleading information about placebos. OBJECTIVE: We aimed to create an informative, scientifically accurate, and engaging website that could be used to improve understanding of placebo effects among patients who might be considering taking part in a placebo-controlled clinical trial. METHODS: Our approach drew on evidence-, theory-, and person-based intervention development. We used existing evidence and theory about placebo effects to develop content that was scientifically accurate. We used existing evidence and theory of health behavior to ensure our content would be communicated persuasively, to an audience who might currently be ignorant or misinformed about placebo effects. A qualitative 'think aloud' study was conducted in which 10 participants viewed prototypes of the website and spoke their thoughts out loud in the presence of a researcher. RESULTS: The website provides information about 10 key topics and uses text, evidence summaries, quizzes, audio clips of patients' stories, and a short film to convey key messages. Comments from participants in the think aloud study highlighted occasional misunderstandings and off-putting/confusing features. These were addressed by modifying elements of content, style, and navigation to improve participants' experiences of using the website. CONCLUSIONS: We have developed an evidence-based website that incorporates theory-based techniques to inform members of the public about placebos and placebo effects. Qualitative research ensured our website was engaging and convincing for our target audience who might not perceive a need to learn about placebo effects. Before using the website in clinical trials, it is necessary to test its effects on key outcomes including patients' knowledge and capacity for making informed choices about placebos.
Item Type: | Article |
---|---|
ISSN: | 1929-0748 |
Uncontrolled Keywords: | consumer health information ; health attitudes ; informed consent ; placebo effect ; qualitative research |
Group: | Faculty of Science & Technology |
ID Code: | 32891 |
Deposited By: | Symplectic RT2 |
Deposited On: | 14 Oct 2019 09:16 |
Last Modified: | 14 Mar 2022 14:18 |
Downloads
Downloads per month over past year
Repository Staff Only - |