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Inspiratory Conductance does not vary with Height, Weight, Body Mass Index, Age, Sex or Spirometric Volumes in Healthy Adults.

Allen, S., Gale, D., Khattab, A. D., Brown, I. and Bagust, J., 2019. Inspiratory Conductance does not vary with Height, Weight, Body Mass Index, Age, Sex or Spirometric Volumes in Healthy Adults. International Journal of Internal Medicine and Geriatrics, 1 (2), 43 - 45.

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Abstract

Introduction and objective: We previously showed that inspiratory conductance (IC) can be calculated from early inspiratory pressure fall and initial acceleration of the inspiratory air column. To characterize IC further we conducted a study to determine whether its value varies with height, weight, BMI, age, sex and lung volumes. Methods: We measured IC, height, weight, FEV1, FVC and PEFR in 147 healthy volunteers’ age 18-50 years. Results: During tidal breathing at rest the mean (SD) IC was 8.31 (3.15) L s-1 kPa-1. No significant correlation was found between IC and height (r=0.04), weight (r=0.142), BMI (r=0.058), FEV1 (r=0.275), FVC (r=0.019), PEFR (r=0.182) or age (r=0.017) and there was no significant difference between men and women. The same was found for IC measured during slow deep breathing and rapid breathing. Conclusion: IC is independent of age, sex, height, weight, BMI and spirometric lung volumes so there is no imperative to correct for those factors in an individual. Within-subject directional changes in IC within the context of a short clinical timeframe might be the best potential for clinical application.

Item Type:Article
ISSN:2689-7687
Uncontrolled Keywords:Inspiratory conductance ; Airflow resistance ; Lung function ; Spirometry
Group:Faculty of Health & Social Sciences
ID Code:33514
Deposited By: Unnamed user with email symplectic@symplectic
Deposited On:26 Feb 2020 14:41
Last Modified:26 Feb 2020 14:41

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