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Measuring the cost-effectiveness of treatments for people with multiple sclerosis: Beyond quality-adjusted life-years.

Hawton, A., Goodwin, E., Boddy, K., Freeman, J., Thomas, S., Chataway, J. and Green, C., 2020. Measuring the cost-effectiveness of treatments for people with multiple sclerosis: Beyond quality-adjusted life-years. Multiple Sclerosis Journal, -. (In Press)

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DOI: 10.1177/1352458520954172

Abstract

BACKGROUND: It is a familiar story. A promising multiple sclerosis (MS) treatment clears the three regulatory hurdles of safety, quality and efficacy, only to fall at the fourth: cost-effectiveness. This has led to concerns about the validity of the measures typically used to quantify treatment effects in cost-effectiveness analyses and in 2012, in the United Kingdom, the National Institute for Health and Care Excellence called for an improvement in the cost-effectiveness framework for assessing MS treatments. OBJECTIVE AND METHODS: This review describes what is meant by cost-effectiveness in health/social care funding decision-making, and usual practice for assessing treatment benefits. RESULTS: We detail the use of the quality-adjusted life-year (QALY) in resource allocation decisions, and set out limitations of this approach in the context of MS. CONCLUSION: We conclude by highlighting methodological and policy developments which should aid addressing these limitations.

Item Type:Article
ISSN:1352-4585
Uncontrolled Keywords:Multiple sclerosis ; cost-effectiveness ; cost-effectiveness analysis ; health-related quality of life ; quality of life ; quality-adjusted life-years
Group:Faculty of Health & Social Sciences
ID Code:34551
Deposited By: Unnamed user with email symplectic@symplectic
Deposited On:16 Sep 2020 14:27
Last Modified:16 Sep 2020 14:27

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