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ToolsArias-Colinas, M., Gea, A., Khattab, A. D., Vassallo, M., Allen, S.C. and Kwan, J., 2022. The Association between Inflammatory Biomarkers and Cardiovascular Autonomic Dysfunction after Bacterial Infection. Applied Sciences, 12 (7), 3484.
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DOI: 10.3390/app12073484
Abstract
Heart rate variability (HRV) is a known measure of cardiac autonomic function. A cardiovascular autonomic dysfunction (CAD), measured as changes in HRV, is usually presented after an infectious process. The aim of the present study is to assess the association between serum inflammatory markers and CAD. For this purpose, 50 volunteers (13 of them recovering from an infection) were recruited and followed-up for 6 weeks. Their serum inflammatory biomarkers (CRP, IL1, IL4, IL6, IL10, and TNFalpha) were quantified throughout those weeks, along with their HRV resting, in response to the Valsalva maneuver, metronome breathing, standing and sustained handgrip. The correlation of within-subject changes in both HRV and inflammatory biomarkers was assessed to evaluate the concurrent changes. An inverse within-subject correlation was found between CRP and HRV in response to the Valsalva maneuver (rho (95% CI):
| Item Type: | Article |
|---|---|
| ISSN: | 2076-3417 |
| Additional Information: | (This article belongs to the Special Issue Biological Markers of Cardiovascular Diseases: Applications and Utility in Clinical Practice) |
| Uncontrolled Keywords: | inflammatory biomarkers; cardiac autonomic dysfunction; heart-rate variability; Creactive protein; interleukins; bacterial infection |
| Group: | Faculty of Health & Social Sciences |
| ID Code: | 36800 |
| Deposited By: | Symplectic RT2 |
| Deposited On: | 04 Apr 2022 09:45 |
| Last Modified: | 04 Apr 2022 09:45 |
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