Unexpected sounds induce a rapid inhibition of eye-movement responses.

Abstract

Unexpected sounds have been shown to trigger a global and transient inhibition of motor responses. Recent evidence suggests that eye movements may also be inhibited in a similar way, but it is not clear how quickly unexpected sounds can affect eye-movement responses. Additionally, little is known about whether they affect only voluntary saccades or also reflexive saccades. In this study, participants performed a pro-saccade and an anti-saccade task while the timing of sounds relative to stimulus onset was manipulated. Pro-saccades are generally reflexive and stimulus-driven, whereas anti-saccades require the generation of a voluntary saccade in the opposite direction of a peripheral stimulus. Unexpected novel sounds inhibited the execution of both pro- and anti-saccades compared to standard sounds, but the inhibition was stronger for anti-saccades. Novel sounds affected response latencies as early as 150 ms before the peripheral cue to make a saccade, all the way to 25 ms after the cue to make a saccade. Interestingly, unexpected sounds also reduced anti-saccade task errors, indicating that they aided inhibitory control. Overall, these results suggest that unexpected sounds yield a global and rapid inhibition of eye-movement responses. This inhibition also helps suppress reflexive eye-movement responses in favor of more voluntarily generated ones.